Andrew Meltzer

Andrew Meltzer

  • Professor of Emergency Medicine
  Email Andrew Meltzer
  202-741-2904
Department: Emergency Medicine
Education
BS, Brown University, 1996
MD, Suny Down State, 2002
Biography

Andrew C. Meltzer, MD, MS, FACEP is a Professor of Emergency Medicine and the Chief of the Clinical Research Section at the George Washington University School of Medicine. Dr. Meltzer received his MD from SUNY Downstate, completed his residency in Emergency Medicine at the University of Maryland and the R Adams Cowley Shock Trauma Center, and completed a fellowship in Clinical Research at the University of Maryland.

He is a Fellow of the American College of Emergency Physicians (ACEP), serves on the ACEP Clinical Policies Committee and the Society of Academic Emergency Medicine (SAEM) Research Committee, and was an author of the SAEM GRACE-2 Guidelines for Abdominal Pain. As the Director of the Clinical Practice Innovation and Entrepreneurship (CPIE) scholarly track, Dr. Meltzer mentors students and faculty in medical innovation.

Dr. Meltzer is the site principal investigator for the NIH SIREN network and has led several major multi-center clinical trials, including studies on abdominal pain, novel diagnostic strategies for gastrointestinal hemorrhage, medical expulsive therapy for renal colic, and acute management of respiratory distress (HYPERACT trial). As Director of the Research Section, he oversees clinical research in the emergency department with a professional team of research coordinators and an active research fellowship program.

He has contributed to national and international guidelines in emergency medicine, including SAEM guidelines for abdominal pain and international guidelines for the management of gastrointestinal bleeding. Dr. Meltzer practices emergency medicine in community, academic, and military hospital settings, ensuring his research remains clinically relevant. He has also served as chief medical officer for two successful healthcare technology companies.

As of this writing, Dr. Meltzer has authored over 60 peer-reviewed publications in PubMed and has an i10-index of 37.

Residency Training:
Residency in Emergency Medicine, University of Maryland

Fellowship Training
Clinical Research, University of Maryland

Certifications:
Board Certified in Emergency Medicine

Professional Societies:
ACEP Clinical Policies Committee
SAEM Research Committee

Special Interests:
POC Diagnostics and Abdominal Pain Emergencies
Gastrointestinal Research

Publications

Papers (In Press)

  • Barshay M, Zang C, Bolden T, Rosenfeld L, Marko K, Sudimack A, Sebastian A, Loganathan A, Ma Y, Meltzer A. Tracking engagement with remote patient monitoring in prenatal care and detection of preeclampsia: a retrospective review. Telemedicine and e-Health. In press 2025.
  • Heidish R, Loganathan A, Bolden T, Meltzer AC. Pilot study of cannabinoid hyperemesis syndrome (CHS) patients treated in the ED: high severity pain and impact on patient reported outcomes. In press 2025.
  • Meltzer AC. Pilot study of recurrent abdominal pain in the ED: low-risk disease associated with high severity pain and frequent opioid administration. Clin Exp Emerg Med. In press 2025.

Papers in Refereed Journals

  • Trevino J, Loganathan A, Abdullah I, Meltzer AC. Community awareness of acoustic gunshot detection systems in Washington, DC. Am J Emerg Med. 2025;S0735-6757(25)00361-4. doi:10.1016/j.ajem.2025.05.040. [Epub ahead of print].
  • Singer AJ, Hollander JE, Kean ER, Ring H, Peacock WF, Soto-Ruiz K, Motov S, et al. Effect of host-protein test (TRAIL/IP-10/CRP) on antibiotic prescription and emergency department or urgent care center return visits: the JUNO pilot randomized controlled trial. Acad Emerg Med. In press 2025.
  • Ray BM, Kelleran KJ, Kaisler MC, Meltzer AC. Emergency department visit frequency among adults with chronic abdominal pain: findings from the 2023 US National Health Interview Survey. Acad Emerg Med. 2025.
  • American College of Emergency Physicians Clinical Policies Subcommittee (Writing Committee) on Asymptomatic Hypertension; Gemme S, Meltzer AC, Byyny R, Diercks DB; Members of the American College of Emergency Physicians Clinical Policies Committee. Clinical policy: a critical issue in the outpatient management of adult patients presenting to the emergency department with asymptomatic elevated blood pressure: approved by the ACEP Board of Directors January 22, 2025. Ann Emerg Med. 2025;86(1):e1-e11. doi:10.1016/j.annemergmed.2024.09.016. PMID: 40543987.
  • Meltzer AC, Loganathan A, Moran S, Shahamatdar S, Dominguez LW, Willis J, Zhang W, Zhang X, Ma Y. A multicenter randomized control trial: point-of-care syndromic assessment versus standard testing in urgent care center patients with acute respiratory illness. J Am Coll Emerg Physicians Open. 2024;5(5):e13306. doi:10.1002/emp2.13306. PMID: 39445121; PMCID: PMC11497039.
  • Yamane DP, Jones CW, Wilkerson RG, Oliver JJ, Shahamatdar S, Loganathan A, Bolden T, Heidish R, Kelly CL, Bergeski A, Whittle JS, Dungan GC 2nd, Maisiak R, Meltzer AC. High-velocity nasal insufflation versus noninvasive positive pressure ventilation for moderate acute exacerbation of chronic obstructive pulmonary disease in the emergency department: a randomized clinical trial. Acad Emerg Med. 2024 Dec 11. doi:10.1111/acem.15038. Epub ahead of print. PMID: 39663589.
  • Makutonin M, Ramdin C, Meltzer A, Mazer-Amirshahi M, Nelson L. Concurrent alcohol and opioid intoxication in emergency department patients leads to greater resource utilization. Subst Use Misuse. 2024;59(4):616-621. doi:10.1080/10826084.2023.2294963. PMID: 38192231.
  • Ramdin C, Makutonin M, Nelson LS, Meltzer AC, Mazer-Amirshahi M. Outcomes and resource utilisation of patients presented to the emergency department with opioid and benzodiazepine poisoning. Emerg Med J. 2024 Jan 22;41(2):114-115. doi:10.1136/emermed-2023-213180. PMID: 37669833.
  • Meltzer AC, et al. Cannabinoid hyperemesis syndrome is associated with high disease burden: an internet-based survey. Ann Emerg Med. 2025 Feb 20. doi:10.1016/j.annemergmed.2025.01.008.
  • Makutonin M, Moghatederi A, Newton S, Ma Y, Meltzer AC. Biliary colic in the emergency department: a state-wide analysis of one-year costs and clinical outcomes. Surg Open Sci. 2023 Feb 10;12:9-13. doi:10.1016/j.sopen.2023.02.002. PMID: 36866121; PMCID: PMC9971543.
  • Meltzer, Andrew C., et al. Magnetically controlled capsule for assessment of the gastric mucosa in symptomatic patients: a prospective, single-arm, single-center, comparative study. iGIE. 2023;2(2):139-147.
  • Choo EK, Strehlow M, Del Rios M, Oral E, Pobee R, Nugent A, Lim S, Hext C, Newhall S, Ko D, Chari SV, Wilson A, Baugh JJ, Callaway D, Delgado MK, Glick Z, Graulty CJ, Hall N, Jemal A, Kc M, Mahadevan A, Mehta M, Meltzer AC, Pozhidayeva D, Resnick-Ault D, Schulz C, Shen S, Southerland L, Du Pont D, McCarthy DM. Observational study of organisational responses of 17 US hospitals over the first year of the COVID-19 pandemic. BMJ Open. 2023 May 8;13(5):e067986. doi:10.1136/bmjopen-2022-067986. PMID: 37156578; PMCID: PMC10410813.
  • Makutonin M, Newton S, Tse J, Moghtaderi A, Ma Y, Meltzer AC. Patients with complicated gallstone disease in the emergency department: clinical impact and cost-effectiveness of emergency department disposition decision. J Am Coll Emerg Physicians Open. 2022 Oct 14;3(5):e12795. doi:10.1002/emp2.12795. PMID: 36254222; PMCID: PMC9562831.
  • Broder JS, Oliveira J E Silva L, Bellolio F, Freiermuth CE, Griffey RT, Hooker E, Jang TB, Meltzer AC, Mills AM, Pepper JD, Prakken SD, Repplinger MD, Upadhye S, Carpenter CR. Guidelines for Reasonable and Appropriate Care in the Emergency Department 2 (GRACE-2): Low-risk, recurrent abdominal pain in the emergency department. Acad Emerg Med. 2022 May 11. doi:10.1111/acem.14495. Epub ahead of print. PMID: 35543712.
  • Goldberg EM, Southerland LT, Meltzer AC, Pagenhardt J, Hoopes R, Camargo CA, Jr., Kline JA. Age-related Differences in Symptoms in Older Emergency Department Patients with COVID-19: Prevalence & Outcomes in a Multicenter Cohort. J Am Geriatr Soc. 2022. doi:10.1111/jgs.17816. PMID: 35460268.
  • Thomas SA, Puskarich M, Pulia MS, Meltzer AC, Camargo CA, Courtney DM, Nordenholz KE, Kline JA, Kabrhel C. Association Between Baseline Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers and Death Among Patients Tested for COVID-19. J Clin Pharmacol. 2022;62:777-782. https://doi.org/10.1002/jcph.2015
  • Goldberg EM, et al. Viral Coinfection is Associated with Improved Outcomes in Emergency Department Patients with SARS-CoV-2. West J Emerg Med. 2021;22(6):1262.
  • Beiser DG, Jarou ZJ, Kassir AA, et al. Predicting 30-day return hospital admissions in patients with COVID-19 discharged from the emergency department: A national retrospective cohort study. JACEP Open. 2021;2:e12595. https://doi.org/10.1002/emp2.12595
  • Meltzer AC, Newton S, Lange J, Hall NC, Vargas NM, Huang Y, et al. A randomized control trial of a multiplex gastrointestinal PCR panel versus usual testing to assess antibiotics use for patients with infectious diarrhea in the emergency department. JACEP Open. 2022;3(1):e12616.
  • Tovar MA, Zwemer CH, Wend CM, Meltzer AC, Sarani B, Phillips JP. Disasters on campus: A cross-sectional survey of college EMS systems’ preparedness to respond to mass casualty incidents. Am J Disaster Med. 2022;16(4).
  • Meltzer AC, Limkakeng AT Jr, Gentile NT, Freeman JQ, Hall NC, Vargas NM, Fleischer DE, Malik Z, Kallus SJ, Borum ML, Ma Y, Kumar AB. Risk stratification with video capsule endoscopy leads to fewer hospital admissions in emergency department patients with low-risk to moderate-risk upper gastrointestinal bleed: A multicenter clinical trial. JACEP Open. 2021 Oct 25;2(5):e12579. doi:10.1002/emp2.12579. PMID: 34723247
  • Jackman SV, Maganty A, Wolfson AB, Burrows PK, MacPherson C, Vargas NM, Kirkali Z, Meltzer AC. Resolution of Hydronephrosis and Pain to Predict Stone Passage for Patients With Acute Renal Colic. Urology. 2022 Jan;159:48-52. doi: 10.1016/j.urology.2021.09.017. Epub 2021 Oct 7. PMID: 34627871.
  • Oliveira J E Silva L, Prakken SD, Meltzer AC, et al. Depression and anxiety screening in emergency department patients with recurrent abdominal pain: An evidence synthesis for a clinical practice guideline. Acad Emerg Med. 2021 Oct. doi:10.1111/acem.14394. PMID: 34665903.
  • Jackman SV, Maganty A, Wolfson AB, Burrows PK, MacPherson C, Vargas NM, Kirkali Z, Meltzer AC. Resolution of Hydronephrosis and Pain to Predict Stone Passage for Patients With Acute Renal Colic. Urology. 2022;159:48-52.
  • Sepulveda JL, Abdulbaki R, Sands Z, Codoy M, Mendoza S, Isaacson N, Kochar O, Keiser J, Haile-Mariam T, Meltzer AC, Mores CN, Sepulveda AR. Performance of the Abbott ID NOW rapid SARS-CoV-2 amplification assay in relation to nasopharyngeal viral RNA loads. J Clin Virol. 2021;140:104843. doi:10.1016/j.jcv.2021.104843. PMID: 33746626; PMCID: PMC7978232.
  • Siegel R, Sullivan N, Monte AA, Vargas NM, Cooper ZD, Ma Y, Meltzer AC. Motivational interviewing to treat substance use disorders in the emergency department: A scoping review. Am J Emerg Med. 2022;51:414-417.
  • Kline JA, Camargo CA Jr, Courtney DM, Kabrhel C, Nordenholz KE, Aufderheide T, Baugh JJ, Meltzer AC, et al. Clinical prediction rule for SARS-CoV-2 infection from 116 US emergency departments 2-22-2021. PLoS One. 2021;16(3):e0248438.
  • Newton S, Zollinger B, Freeman J, Moran S, Helfand A, Authelet K, Meltzer AC. Factors associated with clinical severity in emergency department patients presenting with symptomatic SARS‐CoV‐2 infection. JACEP Open. 2021;2(4):e12453.
  • Lange J, Meltzer AC. Video Capsule Endoscopy Beyond the Gastrointestinal Suite. Gastrointest Endosc Clin N Am. 2021 (accepted).
  • Meltzer AC, Wolfson AB, Mufarrij P, MacPherson C, Montano N, Kirkali Z, Burrows PK, Jackman SV. Analgesic and Opioid Use for Patients Discharged from the Emergency Department with Ureteral Stones. J Endourol. 2021;1067-1071. http://doi.org/10.1089/end.2020.0835
  • Li B, Downen RS, Dong Q, Tran N, LeSaux M, Meltzer AC, Li Z. A Discreet Wearable IoT Sensor for Continuous Transdermal Alcohol Monitoring - Challenges and Opportunities. IEEE Sens J. 2021;21(4):5322-5330. doi:10.1109/jsen.2020.3030254. PMID: 33746626; PMCID: PMC7978232.
  • Han C, Meltzer AC. Man with foreign body in nose. JACEP Open. 2020 May 28;1(4):645-647. doi:10.1002/emp2.12039. PMID: 33000084; PMCID: PMC7493554.
  • Shah N, Chen C, Montano N, Cave D, Siegel R, Gentile NT, Limkakeng AT Jr, Kumar AB, Ma Y, Meltzer AC. Video capsule endoscopy for upper gastrointestinal hemorrhage in the emergency department: A systematic review and meta-analysis. Am J Emerg Med. 2020;38(6):1245-1252. doi:10.1016/j.ajem.2020.03.008. PMID: 32229221.
  • Siegel R, Sarani B, Meltzer AC. Delayed presentation of a firearm injury in a patient with recent use of phencyclidine: A case report. Trauma Case Rep. 2019 Dec 18;25:100272. doi:10.1016/j.tcr.2019.100272. PMID: 31890835; PMCID: PMC6928346.
  • Meltzer AC, Burrows PK, Kirkali Z, Hollander JE, Kurz M, Mufarrij P, Wolfson AB, MacPherson C, Hubosky S, Montano N, Jackman SV. Accuracy of Patient Reported Stone Passage for Patients with Acute Renal Colic Treated in the Emergency Department. Urology. 2020;136:70-74. doi:10.1016/j.urology.2019.10.010. PMID: 31704458; PMCID: PMC7008075.
  • Silverman RA, House SL, Meltzer AC, Hahn B, Lovato LM, Avarello J, Miller JB, Kalfus IN, Fathi R, Raday G, Plasse TF, Yan EC. Bimodal Release Ondansetron for Acute Gastroenteritis Among Adolescents and Adults: A Randomized Clinical Trial. JAMA Netw Open. 2019 Nov 1;2(11):e1914988. doi:10.1001/jamanetworkopen.2019.14988. PMID: 31702802; PMCID: PMC6902785.
  • Barkun AN, Almadi M, Kuipers EJ, Laine L, Sung J, Tse F, Leontiadis GI, Abraham NS, Calvet X, Chan FKL, Douketis J, Enns R, Gralnek IM, Jairath V, Jensen D, Lau J, Lip GYH, Loffroy R, Maluf-Filho F, Meltzer AC, Reddy N, Saltzman JR, Marshall JK, Bardou M. Management of Nonvariceal Upper Gastrointestinal Bleeding: Guideline Recommendations from the International Consensus Group. Ann Intern Med. 2019 Dec 3;171(11):805-822. doi:10.7326/M19-1795. PMID: 31634917; PMCID: PMC7233308.
  • Miller J, House S, Lovato L, Meltzer A, Hahn B, Avarello J, Silverman R. Absence of QT prolongation after administration of a 24-mg bimodal-release ondansetron pill (RHB-102). Am J Emerg Med. 2020;38(9):1827-1832. doi:10.1016/j.ajem.2020.02.057.
  • Barkun AN, Almadi M, Kuipers EJ, Laine L, Sung J, Tse F, Leontiadis GI, Abraham NS, Calvet X, Chan FKL, Douketis J, Enns R, Gralnek IM, Jairath V, Jensen D, Lau J, Lip GYH, Loffroy R, Maluf-Filho F, Meltzer AC, Reddy N, Saltzman JR, Marshall JK, Bardou M. Management of Nonvariceal Upper Gastrointestinal Bleeding: Guideline Recommendations From the International Consensus Group. Ann Intern Med. 2019 Oct 22. doi:10.7326/M19- 1795. [Epub ahead of print] PMID: 31634917.
  • Li A, Tran S, Wang H, LeSaux M, Ma Y, Meltzer AC. Multiplex polymerase chain reaction test to diagnose infectious diarrhea in the emergency department. Am J Emerg Med. 2019;37(7):1368-70.

Industry Relationships and Collaborations

This faculty member (or a member of their immediate family) has reported a financial interest with the health care related companies listed below. These relations have been reported to the University and, when appropriate, management plans are in place to address potential conflicts.

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