Dr. Rama Dwivedi is an adjunct associate professor of medicine in the division of kidney diseases and hypertension. He is a Senior Pharmacologist/Toxicologist in the Division of CardioRenal Drug Products in the Office of New Drugs (OND) at Food and Drug Administration’s Center for Drug Evaluation and Research (CDER). The CardioRenal Division is responsible for the regulation and approval of cardiovascular and renal drug products. Dr. Dwivedi has long standing interest in cardiorenal drug products to those related with epigenetic mechanism toward the treatment of cardiovascular and renal diseases including hypertension, acute kidney and chronic kidney diseases.
In addition to US Food and Drug Administration, Dr. Dwivedi has also an Adjunct Faculty appointment in the Division of Kidney Diseases and Hypertension, Department of Medicine and Biochemistry and Molecular Biology at the George Washington University School of Medicine. Dr. Dwivedi’s interest lies in the role of epigenetic mechanism(s) in AKI, CKD, diabetic nephropathy, hypertension and related cardiovascular diseases (CVDs).
Prior to joining the US Food and Drug Administration in 2008, Dr. Dwivedi served as Associate Professor (Research) in the Department of Pediatrics at the Children’s Memorial Hospital, Northwestern University Medical School since 1995 to 2007. Dr. Dwivedi has published more than 54 peer reviewed articles in the area of pharmacology, toxicology, epigenetics and kidney and hypertension.
Dr. Dwivedi was trained in transgenic knock-out and knock-in molecular biological techniques in Nobel Laureate Mario Capecchi’s laboratory, University of Utah, School of Medicine at Salt Lake City, Utah. Following his training in Mario’s laboratory, Dr. Dwivedi established the Targeted Mutagenesis Facility at the Northwestern University, School of Medicine, and served as Associate Director from 1995 to 2007. During his tenure as Associate Director of the Mutagenesis Facility, Dr. Dwivedi generated more than 27 knockout mouse models for critical diseases.